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From the point of view of cow physiology calving and after calving periods are the most difficult. At that moment various biochemical, endocrine, system changes take place in animal's body that requires realization of all metabolic resources. At this time compensatory mechanisms will be exhausted, because long period of pregnancy preceded calving. However, even after calving, the long-expected rest period for organism does not come - now the cascade of biological processes so as to synthesize colostrum, and then milk are needed for new born calf.

In practice we are faced with array of problems, especially with milk fever and retained placenta in the result of compensatory mechanisms and energy resources exhaustion during pregnancy and calving. There is significant number of theories for explanation of milk fever, but most of them are not proved by experiment and practice. 

It is found that during milk fever the sugar content in blood severely reduces (3-4 times below normal). It served as basis for explanation of milk fever occurrence as a result of hypoglycemia. Some authors consider pancreas hyperfunction as the cause of milk fever, in which, a large amount of insulin that provokes hypoglycemia is produced under the influence of hyperemia. Special studies demonstrated that post injection of insulin we can see typical picture of cow milk fever. After injection of 40 ml of 20% glucose solution, all disease symptoms quickly disappear.  Milk fever occurrence is connected with hypocalcemia, hypophosphatemia and hypomagnesemia, which appear in the result of inhibition of parathyroid glands functions due to their hyperemia during calving and total nervous overexcitement. 

There are significant changes in carbohydrate and protein metabolism under the milk fever.

Retained placenta is met among all animals, but due to structure peculiarity and connection between its fetal and maternal parts it is more common for cows. Depending on whether all fetal membranes expel from the animal reproductive tracts, retention can be complete – when all fetal membranes remain in the parturient canal – and incomplete (partial) when particular parts of chorion or single placentas (cow) retain in the uterine cavity. Direct causes of the retained placenta are uterine atony and insufficient labor pain tonicity, adherence of fetal placenta part with maternal due to inflammatory processes in endometrium or fetal chorion.  

Biocom Ltd. specialists developed specialized water soluble feed additive for cows after calving named as ReeStabil in order to reduce likelihood of occurrence of above mentioned pathologies and also for the prevention of negative energy balance development and stimulation of compensatory physiological mechanisms.

Composition and properties of ReeStabil:

1.     Chelated micronutrients - high bioavailability, optimization of the endocrine and enzyme systems, safe application.

2.     Salts of microelements – normalization of proteins, fats and carbohydrates metabolism; development of rumen microflora, pH rumen regulation. 

3.     Vitamin D3 together with salts of calcium and phosphorus – prevention of hypocalcaemia and hypophosphatemia. Prophylaxis of rumen acidosis. 

4.     Vitamins – stimulation of the immune system and metabolic processes, antioxidant protection, prevention of  uterine subinvolution and retained placenta.

5.     Energy components - prevention of ketosis and milk fever and negative energy balance.

6.     Prebiotics – stimulation of the development of symbiotic  microflora

7.     Natural attractants - cows willingly drink the finished product in large quantities. Prophylaxis of displaced abomasum. Does not require forced drenching.

Accurate confirmation of reduction of milk fever and retained placenta occurrence was obtained in the result of conducted trials on different commercial dairy farms. Trials were carried out on 200 cows 3-5 lactation. Animals of the experimental group obtained dissolved in water feed additive ReeStabil at once after calving. The control group was subjected to standard veterinary interventions which were established on the farms. Application of ReeStabil enables to reduce of occurrence of milk fever by 65% and retained placenta by 50% (Figures 1 and 2). 


Besides, after calving animals refreshed more quickly, willingly drank water and ate feed, lactation appeared earlier. According to the biochemical values dynamic, changes were observed that are typical for normalization of metabolic processes development. Thus in the group which received ReeStabil  it was registered  increase of level of glucose, total protein, albumin, cholesterol, decrease of transaminases, bilirubin, urea, creatinine (Table 1) .

ReeStabil – an innovative water soluble feed additive for cows in the first hours after calving.

Vitamin and mineral composition of the additive is selected taking into account increased physiological stress for cows, it ensures rapid recovery of the animal after calving, reduces the risk of milk fever and retained placenta. Chelated micronutrients have high bioavailability, and that optimizes the endocrine and enzyme systems of the cow organism. Salts of microelements in combination with prebiotic normalize the metabolism of proteins, fats and carbohydrates; stimulate the development of symbiotic rumen microflora, which creates conditions for its normal operation; contributes to the high feed conversion in the after calving period. Energy components make up for the energy deficiency and neutralize negative energy balance, without risk of rumen acidosis occurrence. ReeStabil has pleasant taste and specific odor which stimulates appetite. Animals drink the finished product up to 20 liters willingly, that prevents a common complication such as abomasum displacement and provides a good start to lactation in the after calving period.

Veterinary physician
Dmitry Voloshin



Water-soluble feed additive for cows after calving is a complex of biologically active substances, macro and micro elements, energy substrates, selected in a special ratio required for the cows in the first hours after calving.